Translational Research Award

  • The Translational Research Award supports research projects with a clearly defined pathway to achieving patient benefit.  
  • Its goal is to help to accelerate the translation of scientific findings to the early stages of development of new therapies, devices, and diagnostics. 
  • We welcome projects that have robust commercial potential, likely to attract large scale follow-on funding from other charitable, statutory or industry funders.

Please note Stage 1 applications to this funding scheme will open on 1st October 2021 and close on 31st October 2021. Application forms and accompanying guidance will be published on this page when the grant round opens on 1st October. 

If you have any questions or require any further information about this funding scheme, please contact grants@sightresearchuk.org.

Am I eligible to apply?

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In order to apply for any of our funding schemes:

  • Applicants must be UK based university researchers, or NHS based clinicians and clinical researchers, or allied healthcare professionals.
  • We accept applications for projects that will be carried out across multiple institutions, but the funding will be awarded to the lead applicant’s host institution.
  • The lead applicant’s contract of employment must cover the full duration of the proposed project.

What makes a project eligible for the award?

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Eligible projects must:

  • Be based on unmet clinical need.
  • Aim to generate lead candidates for therapeutic applications.
  • Be relevant to and highly promising in the clinical setting (these are not early stage, proof of concept studies, instead they have already shown that the idea might be used as therapy in man).
  • Be focused on assessing properties such as potency, efficacy, selectivity, or bioavailability of compounds identified by previous research as potentially strong candidates for therapeutic applications.
  • Have a clear pathway to apply for funding such as the MRC Confidence in Concept, MRC Development Pathway Funding Scheme type funding and other similar funding schemes.

What can I apply for?

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Applications can include:

  • Developing candidate therapeutic entities, such as potential new drugs.
  • Pre-clinical testing of novel therapeutic entities (e.g. potential new drugs and devices).
  • “Repurposing” clinical studies – using existing therapies for new indications in eye diseases.
  • Developing and testing novel devices.
  • Developing and testing diagnostics (including biomarker validation).
  • All research should strengthen confidence that a target or therapeutic approach will be applicable to eye conditions.

What is the value of the award?

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  • Up to £150,000
  • Up to 24 months

What does the award pay for?

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The grant can be used flexibly to meet several types of expenditure:

  • Contribution towards the salaries of researchers working primarily on the project, project consumables.
  • Any other direct costs of the translational projects, such as a contribution towards equipment needed for the research project.
  • Subcontracting external input for the production of compounds, viral vectors, etc.

Does the award pay for indirect costs?

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No, it doesn't. Our funding can only pay for the direct costs of the project. 

However, because Sight Research UK is a member of the Association of Medical Research Charities, grant holders can apply for indirect costs from other sources, depending on the nature of the research undertaken:

What projects are not eligible for the award?

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The Translational Research Award is not for:

  • Fundamental or basic research into the causes of eye conditions.
  • Disease modelling research.
  • Projects with no clear pathway to patient benefit.
  • PhD studentships.
  • Salaries of staff between posts/funding (i.e. as “bridging” funds).
  • General consumables.
  • General support for a research group.
  • The development of software.
  • The development of non-therapeutic or non-diagnostic devices.

What is the application assessment process?

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Applications are assessed in two stages:

  • Stage 1: Applications are a brief expression of interest outlining the proposed project. These are assessed by relevant members of our independent Research Advisory Board depending on their expertise. Successful applicants are invited to submit a full application within five weeks of the Stage 1 deadline.
  • Stage 2: Stage 1 applications are assessed within a week of Stage 1 deadline. Following notification of Stage 1 outcome, applicants have four weeks to submit their Stage 2 application.
  • External peer review: Applications are assessed by up to four external peer reviewers per application. These are relevant experts drawn from the fields of translational research, clinical research, clinical practice, and industry and are selected to match their expertise to the proposed project. We will do whatever possible to avoid bias either for or against the applicant and/or the host institution. Applicants are invited to suggest names of peer reviewers from whom we should not seek a review.  External peer reviewers have 6 weeks to return their reviews.
  • Rebuttal: Applicants have the opportunity for rebuttal following receipt of external peer reviews. Any rebuttal must be received within ten days of request from the Sight Research UK Grants Team.
  • Research Advisory Board meeting: All external peer reviews and applicants’ rebuttals are sent to the Research Advisory Board at least three weeks prior to their meeting. Research Advisory Board members are asked to prepare for their meeting by pre-scoring all applications to facilitate discussion on the day. All Stage 2 applications are considered at the same Research Advisory Board meeting.
  • Trustees Board meeting: The Chair of the Research Advisory Board attends the Sight Research UK Board of Trustees meeting to report the advice on funding recommendations from the Research Advisory Board. The Trustees make their grant-making decisions based on the expert advice and on the financial capacity of the organisation at that time. Occasionally, the Trustees will offer to undertake proactive fundraising for projects that, although judged fundable by the Research Advisory Board, exceed the financial capacity of the organisation.
  • Feedback: Following the Board of Trustees’ decision, the Grants Team provides feedback to all applicants, whether successful or unsuccessful. Wherever helpful, we share the views of the Research Advisory Board and of the external peer reviewers who reviewed the applications. Grant Award contracts are issued to all successful candidates and the Grants Team liaises with the award holders throughout the life of the award.

For all enquiries about our research funding, please contact grants@sightresearchuk.org or call 0117 325 7757.